Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimer’s Disease: Antiapoptosis and Antioxidation

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Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimer's Disease: Antiapoptosis and Antioxidation

Armillaria mellea, an edible fungus, exhibits various pharmacological activities, including antioxidant and antiapoptotic properties. However, the effects of A. mellea on Alzheimer's disease (AD) have not been systemically reported. The present study aimed to explore the protective effects of mycelium polysaccharides (AMPS) obtained from A. mellea, especially AMPSc via 70% ethanol precipitation...

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Chemical compositions and antioxidant activities of polysaccharides from the sporophores and cultured products of Armillaria mellea.

Armillaria mellea is a traditional Chinese medicinal and edible mushroom. Many cultured products of A. mellea have been used to develop commercial medicines in recent years. The chemical composition and activities of the major bioactive chemical components-polysaccharides-may be different because of differences in the raw materials used. Four polysaccharides (SP, CMP, CFBP and CFMP) were obtain...

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Analysis of indole compounds in Armillaria mellea fruiting bodies.

A TLC method with densitometric detection for identification and quantitation of indole compounds in methanolic extracts of fruiting bodies of Armillaria mellea (Vahl.) P. Kumm. (Basidiomycota)--Honey mushroom has been developed. The TLC method with densitometric detection was validated for determination of tryptamine and serotonin contents. The use of this chromatographic-densitometric method ...

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INTRINSIC FLUORESCENT COMPOUNDS IN ARMILLARIA MELLEA; HYPHAE AND RHIZOMORPH

The organic solvent extraction of Armillaria mellea showed different highly intrinsic fluorescent compounds either in rhizomorph or in hyphae (F , F , F , MF , MF and MF ). The characterization of ultraviolet and fluoro-spectrophotometry of these compounds has been exhibited. Thin layer chromatography and fluorescent spectrum of hyphae and rhizomorph indicated an additional compound (FH) ...

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Armillaria mellea: phenolic content, in vitro antioxidant and antihyperglycemic effects.

UNLABELLED Armillaria mellea, known as honey mushroom, has been used both as food and medicine. AIM In this work, the ethanolic and hydromethanolic extracts from Armillaria mellea fruiting bodies were investigated for their phenolic content, antioxidant and antihyperglycemic effects (in vitro studies). MATERIAL AND METHODS The total phenolics were quantified using Folin-Ciocalteu assay. The...

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ژورنال

عنوان ژورنال: Oxidative Medicine and Cellular Longevity

سال: 2017

ISSN: 1942-0900,1942-0994

DOI: 10.1155/2017/4184562